What is Hoffmann’s sign or Hoffmann’s Reflex? Hoffmann’s sign is a test for pathological disorder in upper motor neuron reflex as seen in cervical myelopathy when the spinal cord in the cervical spine gets compressed and chances are that the patient will exhibit pathological reflexes. The Hoffmann’s sign is also known as a digital reflex, snapping reflex, Jacobson sign and trauma sign. It clearly demonstrates the lesion in the pyramidal tract even with asymmetric clinical findings along with presence of different reflexes. According to Grivalja et.al from 2015 it has a sensitivity of 59 and a specificity of 49%. How to Perform Hoffmann’s Sign Test · The patient may be sitting or standing. support the patient's hand so that it is completely relaxed, with the fingers partially flexed. Hold the patient hand gently and firmly, Then grasp the patient's middle figure proximal to the distal interphalangeal joint. Then flick the patient's nail of the midd